Loup garous were more powerful cousins of the standard werewolves who were affected by an extremely virulent type of lycanthropic curse.

Like other lycanthropes, loup garous were shapechangers who could shift between the humanoid, a man-wolf shape, and fully lupine form that of a large wolf. In their hybrid form, an average loup garou appeared exceptionally muscular, covered in thick wolf fur, and stood at 7 feet (2.1 meters) tall. They had a short tail, wolf-like legs, and head. While in man-wolf shape, they walked upright, like most humanoids, and had agile hands with opposable thumbs. Unlike the full-wolf shape, they could speak in the hybrid form. However, their voices sounded deep and hoarse. Both hybrid and wolf shapes allowed them movement speed far superior to that of a humanoid. The wolf form looked similar to a large worg, while mountain loup garou appeared even bigger than their lowland cousins.